Modified Thoracoabdominal Nerve Block(M-TAPA) in Pediatric Laparoscopic Appendectomies

Gulhane Training and Research Hospital

Status: Invitation-only

Conditions: Laparoscopic Surgery; Pediatrics; Local Anesthetic; Regional Anesthesia; Post Operative Pain

Treatments: Procedure: M-TAPA Block; Procedure: Local anesthetic infltration to port sites

Study type: Interventional

Funder types: Other

Identifiers

NCT06039150

GULHANEELAERTEN

Details and patient eligibility

About

To compare the effect of M-TAPA block and port-site local anesthetic infiltration on postoperative pain in pediatric laparoscopic appendectomies. The main questions it aims to answer are:

• Is M-TAPA block more effective in reducing pain?
• How M-TAPA block affects the use of rescue analgesics in the postoperative period? Participants will have the same anaesthetic agents during surgery, before extubation they will have same analgesic agent for postoperative pain. Participants in the M-TAPA group will undergo USG-guided M-TAPA block bilaterally with % 0.025 Bupivacaine max dose of 2 mg/kg by the same experienced anesthesiologist before extubation. Participants in the LAI group will be administered 0.025% Bupivacaine at a maximum dose of 2mg/kg divided equally and administered by the surgeon at 3 port entry sites before the patient is extubated.

Enrollment: 52 estimated patients

Sex: All

Ages: 7 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with American society of Anesthesiologists (ASA) physical status I-II,
• Patients which will undergo Laparoscopic appendectomy due to the diagnosis of acute appendicitis,
• Patients whose parents or legal heirs have consented to participate in the study

Exclusion criteria

• Patients with Society of Anesthesiologists (ASA) III-IV status,
• Patients whose parents or legal heirs' disapproval,
• Patients inability to cooperate,
• Patients who have allergy to any of the medications used in the study,
• Patients with perforated appendix
• When the Laparoscopic surgery returns to open shape

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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52 participants in 2 patient groups

M-TAPA group

Experimental group

Description:

The group to be administered 0.025% Bupivacaine by the anesthesiologist bilaterally in M-TAPA block with a maximum dose of 2 mg/kg before extubation.

Treatment:

Procedure: M-TAPA Block

LAİ group

Active Comparator group

Description:

The group to be divided and administered 0.025% Bupivacaine with a maximum dose of 2 mg/kg by the surgeon to 3 port entry sites before extubation

Treatment:

Procedure: Local anesthetic infltration to port sites