Modulating Stress-Reactivity by Real-Time Multimodal Functional Neuroimaging Based Neurofeedback
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About
The overall goal of the outlined study is to establish a Real-Time (RT) functional Magnetic Resonance Imaging (fMRI) Neurofeedback (NF) (RT-fMRI-NF) protocol aiming at modulating neural, endocrine, and subjective reactivity to psychosocial stress.
Full description
The overall goal of the outlined study is to establish an RT-fMRI-NF protocol aiming at modulating neural, endocrine, and subjective reactivity to psychosocial stress. More specifically, the investigators pursue the following goals: a) to evaluate whether neural and subjective stress-reactivity can be modified by training volitional control over targeted brain activity by means of RT-fMRI-NF; b) to evaluate whether neuromodulation by means of RT-fMRI-NF can be used as a new way to modulate hormone-release into the periphery; and c) to evaluate whether the efficacy of neuromodulation by RT-fMRI-NF can also be reflected on EEG data as well as the autonomic nervous system (ANS) measured by heart rate variability (HRV).
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Inclusion criteria
- Sufficient spoken and written knowledge of English
- Right-handedness
- Ability to participate in study procedures
Exclusion criteria
- Present or past psychological or psychiatric therapy
- Major or unstable general medical conditions
- Presence of cardiovascular disease
- Current intake of any medication interfering hormonal assessments
- History of major cerebral injury
- Medical MRI contraindication
Trial design
Primary purpose
Allocation
Interventional model
Masking
0 participants in 2 patient groups
Trial contacts and locations
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Central trial contact
Jong-Hwan Lee, Prof.
Data sourced from clinicaltrials.gov
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