Modulation of Painful Perception (MODOU)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Healthy

Treatments: Device: thermal stimulation delivered by a thermode.; Other: functional MRI

Study type: Interventional

Funder types: Other

Identifiers

NCT02528578

1208141

2012-A01232-41 (Other Identifier)

Details and patient eligibility

About

The objective of the study is to evaluate in healthy volunteers, the influence of empathy on pain perception.

It is widely accepted in the clinical management that the feeling of listening to the patients' pain would have a favorable influence on the pain, and conversely, the lack of listening would be aggravating.

In this study, the volunteer will receive painful thermal stimuli in empathetic context (l, empathetic or non-empathetic) Two situations will oppose, one where the examiner neglect or minimize the suffering of the voluntary and the other or the contrary, the subject will receive empathy.

The first part of the project is to verify that the pain is influenced by the empathetic context. The second part will be conducted functional MRI, which should isolate the brain regions affected by other people's empathy for pain.

Enrollment: 74 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Right handed

Exclusion criteria

• Pregnant or lactating women,
• Against-indications to MRI
• Drug intake of less than 12 hours,
• Neurological history or deficits, psychiatric, auditory or visual.
• Decline to participate

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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74 participants in 1 patient group

healthy volunteers

Experimental group

Treatment:

Other: functional MRI

Device: thermal stimulation delivered by a thermode.