Moisturization and Skin Hydration Study

University of British Columbia

Status: Not yet enrolling

Conditions: Atopic Dermatitis (Eczema); Atopic Dermatitis (AD)

Treatments: Behavioral: Moisturizing after towel drying; Behavioral: Moisturizing while in shower/bath

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT07270965

H25-02646

Details and patient eligibility

About

Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. The goal of this clinical study is to evaluate the preference of moisturizing while showering/bathing compared to after towel drying in adolescents aged 12-18 with eczema. The main question it aims to answer are:

• Which moisturization technique is preferred: while showering/bathing or after towel drying?
• How do these techniques affect investigator-assessed eczema severity, patient-reported itch scores, and objective skin hydration measurements?

Researchers will compare applying moisturizer while in the shower/bath to after towel drying and to which technique is preferred among participants and if there are different effects on eczema and skin hydration.

Participants will:

• Apply moisturizer while showering/bathing for one month and after towel drying for one month.
• Complete questionnaires on moisturization technique, skin feel, and itchiness.
• Undergo skin hydration measurements using a Corneometer® CM825 device.

Enrollment: 30 estimated patients

Sex: All

Ages: 12 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants must have a diagnosis of atopic dermatitis/eczema.
• Participants must be between the age of 12-18.
• Participants must be able to bathe independently.
• Participants will be English speaking and able to complete questionnaires.

Exclusion criteria

• Participants who use topical corticosteroids between one inch above the wrist and 1 inch below the elbow from 1 month on both arms prior to the study until the final visit.
• Participants who have a known allergy to the moisturizer cream (Cerave Moisturizing Cream) provided.

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Moisturizing while in shower/bath

Experimental group

Treatment:

Behavioral: Moisturizing while in shower/bath

Moisturizing after towel drying

Experimental group

Treatment:

Behavioral: Moisturizing after towel drying