Molecular and Cellular Profiling of Uterine Lavage Collected During Gynecologic Surgery

Stanford University

Status

Enrolling

Conditions

Uterine Cancer

Gynecological Surgery

Gynecologic Cancer

Gynecologic Disease

Treatments

Procedure: Uterine Lavage

Study type

Interventional

Funder types

Other

Identifiers

NCT07044505

IRB-77882

Details and patient eligibility

About

This study is a designed as a to test the clinical and technical feasibility of using this novel uterine lavage collection catheter to collected UL samples from up to 50 individuals undergoing gynecologic surgery and to describe the cellular composition of these samples. In order to do this, it is a prospective consecutively-enrolled cohort of 50 participants, all of who will receive the intervention of uterine lavage collection.

Enrollment

50 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Undergoing gynecologic surgery with Stanford Healthcare
Intact uterus and cervix
At least one intact fallopian tube and ovary (on the same side)
Aged 18 years or older
Ability to understand and the willingness to provide written informed consent.

Exclusion criteria

Known endometrial or cervical cancer or endometrial or cervical intraepithelial neoplasia
Status post bilateral salpingectomy or tubal ligation
Lack of consenting capacity
Positive preoperative pregnancy test
Active uterine bleeding (i.e. menses, etc.)
Intrauterine device in place
Non-English speaking (requires interpretor)