Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-small Cell Lung Cancer

University Hospital, Strasbourg, France

Status: Completed

Conditions: Lung Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT00213733

3207

Details and patient eligibility

About

This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).

Full description

Genetic: It is a prospective study during two years with three years for follow-up. No control group is recruited.

Enrollment: 150 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes.
• Informed consent is required.

Exclusion criteria

• Another cancer
• Chemotherapy before surgical treatment