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Molecular Characterization of Spinal Tissue

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Mayo Clinic

Status

Invitation-only

Conditions

Spinal Diseases

Treatments

Other: Waste tissues are collected at the time of spinal surgery.

Study type

Observational

Funder types

Other

Identifiers

NCT03492372
14-008177

Details and patient eligibility

About

The researchers are trying to identify molecular mechanisms that control spine deformity and degenerative changes that can be used for therapeutic strategies.

Full description

Discarded surgical material from spinal procedures is collected. RNA analysis and other tests on the tissue is performed to determine markers of pathologic disease and to develop pharmacologic treatment strategies for pediatric spinal disorders.

Enrollment

300 estimated patients

Sex

All

Ages

1 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Children and adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure. Material from adults may be collected as a control group.

Exclusion criteria

  • Surgeries where spinal tissues are not being removed.

Trial design

300 participants in 1 patient group

Spine patients
Description:
Patients undergoing spine surgery where spinal tissue is discarded/removed will be recruited. Tissue samples will be used to look at normal and pathologic molecular signatures.
Treatment:
Other: Waste tissues are collected at the time of spinal surgery.

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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