Molecular Epidemiology of Enteroviruses Detected at the Virology Laboratory of Brest University Hospital During the Period 2018-2024: Retrospective Analysis of an Atypical Meningitis Epidemic in 2024 (BrEcho9Men)

Regional University Hospital Center (CHRU)

Status: Active, not recruiting

Conditions: Enterovirus Infections; Meningitis, Viral; Meningitis Enterovirus; Echovirus 9

Study type: Observational

Funder types: Other

Identifiers

NCT06922474

29BRC25.0054 - BrEcho9Men

Details and patient eligibility

About

This study is being done to learn more about enterovirus infections detected in the cerebrospinal fluid of patients at CHU de Brest. Researchers will analyze medical records and laboratory data collected between 2018 and 2024. They will look at how these infections present in patients, and whether a specific virus type, called Echo-9, may be associated with different clinical features or represent an emerging variant.

Enrollment: 270 estimated patients

Sex: All

Ages: Under 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cerebrospinal fluid (CSF) sample positive for enterovirus by RT-PCR between January 1, 2018 and December 31, 2024 , performed at the virology laboratory of CHU de Brest.
• No documented opposition to the use of medical data for research purposes.

Exclusion criteria

• Patients under legal protection (guardianship, curatorship, etc.)
• Refusal to participate in the study