Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis

Wuhan University

Status: Unknown

Conditions: Cervical Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT00889902

320.6740

Details and patient eligibility

About

The purpose of this study is to:

1. make p16INK4A as a cervical cancer screening of tumor markers, cytology improve existing diagnostic sensitivity, specificity, repeatability and validity, so as to effectively prompted the early discovery and diagnosis of cervical cancer.
2. reduce screening costs, screening and benefits into quantitative evaluation, for our country to develop cervical cancer prevention and control strategy to provide a reliable theoretical basis.

Full description

1. To carry out large-scale prospective randomized controlled clinical study to evaluate the "cytological molecular markers Detect + P16INK4A" methods of screening accuracy and reliability, as well as the screening method of the biological effects.
2. Markov set up mathematical model of screening tests to quantify the inputs and the evaluation proceeds. With a view to optimize and perfect a simple, convenient, practical and efficient program of cervical cancer screening.

Enrollment: 200 estimated patients

Sex: Female

Ages: 25 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Married women aged 25 to 65-year-old with risk factors
• No tumor and pelvic radiation therapy history
• Non-pregnant women at present