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This study will investigate the molecular mechanisms of atypical-antipsychotic induced insulin resistance. This will be accomplished by administering olanzapine or placebo to healthy subjects for 7 days and analyzing genetic and protein changes in peripheral tissues known to play an important role in insulin resistance pathophysiology.
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Inclusion and exclusion criteria
We will include persons that meet the following criteria:
The following persons will be excluded:
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Interventional model
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31 participants in 2 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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