Molecular Mechanisms of Fibrillin/LTBP Superfamily in Renal Fibrosis and Cardiorenal Syndrome

National Taiwan University

Status: Enrolling

Conditions: Renal Fibrosis, CKD

Study type: Observational

Funder types: Other

Identifiers

NCT05012228

202101074RINC

Details and patient eligibility

About

This project is to understand the LTBP4 expression in human renal fibrotic tissues. The investigators will exam major location of LTBP4 expression and check any similar or discrepancy in renal fibrosis with different etiologies.

Full description

The investigators will obtain the residual renal tissues with different etiologies and check the expression of LTBP4. The location and quantitation of LTBP4 in renal tissues will be checked. It will be great to understand the association between the severity of fibrosis and the expression of LTBP4 and other matrix proteins.

Enrollment: 30 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Abnormal kidney function, proteinuria, hematuria

Exclusion criteria

• N/A