Molecular Mechanisms of Tooth Eruption

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Tooth Eruption

Treatments: Procedure: Tooth extraction

Study type: Observational

Funder types: Other

Identifiers

NCT04675203

7946

Details and patient eligibility

About

The main objective is to study the expression of molecules involved in tooth morphogenesis and eruption in healthy patients, and then to compare them with the results in patients with abnormalities of eruption (results obtained via a collection of biological samples of rare diseases already authorized).

Enrollment: 50 estimated patients

Sex: All

Ages: 12+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient over 12 years old who has given his consent
• Patient whose legal representatives have given their consent for the use of operating waste destined for incineration
• Patient undergoing oral surgery at the University Hospitals of Strasbourg, at the origin of the production of surgical waste such as teeth and bone fragments
• Patient affiliated to a social security system

Exclusion criteria

• Refusal to participate
• Patient with chronic systemic pathology
• Patient under long-term drug treatment
• Patient presenting a rare pathology with oral manifestation
• Patient with a history of chemotherapy or head and neck radiotherapy
• Non-French speaking patient / inability to give informed information
• Patient under guardianship, curatorship or legal protection

Trial design

50 participants in 1 patient group

Normal tooth eruption

Treatment:

Procedure: Tooth extraction