Molecularly Aided Stratification for Tumor Eradication Research (NCT-MASTER)

German Cancer Research Center

Status: Enrolling

Conditions: Multiomics; Rare Cancers

Study type: Observational

Funder types: Other

Identifiers

NCT05852522

TMO0001

Details and patient eligibility

About

NCT/DKFZ/DKTK MASTER is a prospective, continuously recruiting, multicenter observational study for biology-guided stratification of adults with rare cancers, including rare subtypes of common entities, using comprehensive molecular profiling, and clinical decision-making in a multidisciplinary molecular tumor board.

Enrollment: 10,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Rare cancer (Incidence <6/100,000 persons/year) or Rare subtype of a more common entity (case-by-case decision; example: pancreatic ductal adenocarcinoma without KRAS mutation)

Metastatic and/or locally advanced cancer with no curative therapy option and indication for systemic therapy

Exclusion criteria

Severe neurological or psychiatric disorder interfering with the ability to give oral and written informed consent