Molekule for Allergic Rhinitis/Asthma

Molekule

Status: Terminated

Conditions: Asthma; Allergic Conjunctivitis; Allergic Rhinitis

Treatments: Other: Active air purifier in respiratory allergies/asthma; Other: Sham air purifier

Study type: Interventional

Funder types: Industry

Identifiers

NCT03627689

Molekule-052018

Details and patient eligibility

About

Exposure to airborne allergens and pollutants is linked to symptom severity of allergies, asthma and other respiratory problems. In this study an air purifier using photo-electrochemical oxidation technology (PECO) will be used in the home environment of study participants. The investigator will assess the reduction of symptoms from allergic rhinitis/conjunctivitis and asthma.

Full description

The purpose of this study is to assess the efficacy of the portable PECO air purifier in reducing symptoms from allergic rhinitis and asthma. Using a randomized, double blinded placebo, controlled trial we will be then able to assess if there are any changes after the use of the PECO air purifier after completing an initial baseline survey & comparing to the exit survey. This is a double-blind study, which means that neither the participant nor the investigator knows which device is being used until after the trial is over.

Enrollment: 49 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Chronic allergic rhinitis and/or conjunctivitis by history
2. History of adult asthma requiring medications now or in the past
3. Age ≥18
4. CARAT score less than 24

Exclusion criteria

1. Participant is <18 years-old
2. Use of systemic corticosteroids within 14 days of study initiation
3. Treatment with biologic agents or allergen immunotherapy
4. Treatment with other immunomodulators (cyclosporine, azathioprine, hydroxychloroquine, etc)
5. Sensitive to fan sound or blue/purple light at night time

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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49 participants in 2 patient groups

Active air purifier arm

Experimental group

Description:

Active portable air purifier for 1 month at bedside

Treatment:

Other: Active air purifier in respiratory allergies/asthma

Sham air purifier arm

Sham Comparator group

Description:

Placebo portable air purifier for 1 month at bedside

Treatment:

Other: Sham air purifier