Monitoring Brain Waves in Response to Visual and/or Auditory Stimulation in Parkinson's Disease Patients

Rambam Health Care Campus

Status: Unknown

Conditions: Parkinson's Disease

Treatments: Behavioral: visual stimuli; Behavioral: Visual and auditory stimuli; Behavioral: Auditory stimuli; Behavioral: Baseline

Study type: Interventional

Funder types: Other

Identifiers

NCT02768896

0182-16RMB

Details and patient eligibility

About

Voltage fluctuation as a result of brain activity will be recorded into the computer using an EEG device.

Full description

Patients with Parkinson's disease may have gait disturbances including freezing of gait. Visual and auditory stimuli may improve gait. Investigators will analyze brain wave during walking while giving the subject different stimuli.

The voltage fluctuation (in hundreds of microvolts) will be recorded using the EEG cap and amplifier into a computer.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with Parkinson's disease that are ambulatory and can sign a written informed consent

Exclusion criteria

• Patients with Parkinson's disease who are not ambulatory
• Patients with dementia
• Patients that are blind
• Patients that have severe hearing impairment

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 4 patient groups

Baseline

No Intervention group

Description:

Patients will walk naturally with EEG measuring brain waves

Visual stimuli

Experimental group

Description:

Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses

Treatment:

Behavioral: Baseline

Behavioral: visual stimuli

Auditory stimuli

Experimental group

Description:

Patients will walk naturally with EEG measuring brain waves while hearing an auditory stimuli

Treatment:

Behavioral: Baseline

Behavioral: Auditory stimuli

Visual and auditory stimuli

Experimental group

Description:

Patients will walk naturally with EEG measuring brain waves while seeing a grid through glasses and hearing an auditory stimuli simultaneously

Treatment:

Behavioral: Baseline

Behavioral: Visual and auditory stimuli