Monitoring Intermittent Fasting for Human Optimization Using Wearable Technology: An N-of-1 Study

Institute for Digital Medicine (WisDM)

Status

Not yet enrolling

Conditions

Healthy

Digital Health

Intermittent Fasting

Treatments

Device: Wearables

Behavioral: Glucose-Ketone Index (GKI) monitoring

Other: Interviews

Behavioral: Fitness intervention

Dietary Supplement: Supplements

Behavioral: Generative AI

Behavioral: Mediterranean-inspired diet

Diagnostic Test: Stool tests

Device: Airofit

Other: Digital dynamometer

Behavioral: 18h fasting

Behavioral: 48h fasting

Behavioral: Continuous Glucose Monitoring (CGM)

Diagnostic Test: Saliva tests

Behavioral: Three meal phase

Behavioral: Cold & heat intervention

Diagnostic Test: Blood tests

Study type

Interventional

Funder types

Other

Identifiers

NCT06630637

HO_prospective

Details and patient eligibility

About

There is a growing interest in personalized health strategies, including diet, exercise, and fasting regimens, to enhance metabolic fitness. Recent research indicates that intermittent fasting (IF) is useful not only for weight management, but also for energy production and improvement of metabolic well-being.

IF can potentially reduce systemic inflammation and help to prevent chronic diseases. IF research can also help athletes sustain performance during fasting periods. This prospective study aims to investigate the effects of a human optimization program on an individual's metabolic health and overall well-being.

This research examines the correlations between continuous glucose monitoring, ketone measurement, exercise routines, heat/cold interventions, diet, supplements and intermittent fasting patterns. The study involves a single participant -the principal investigator- who will adhere to a personalized regimen involving wearable monitoring of metabolic changes, training and intermittent fasting. This research seeks to understand the potential relationships between these factors, contributing to the emerging knowledge on individualized health optimization.

Enrollment

1 estimated patient

Sex

Male

Ages

21+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

The principal investigator is the sole participant in this N-of-1 trial: a healthy individual with no chronic diseases or conditions affecting metabolic health.

Exclusion criteria

The principal investigator is the sole participant in this N-of-1 trial.

Trial design

Primary purpose

Basic Science

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

1 participants in 1 patient group

Personalized Health Intervention Arm

Experimental group

Description:

This arm involves the the single participant following a personalized regimen that includes intermittent fasting, exercise routines, heat/cold interventions, diet modifications, and supplementation. The participant will engage in continuous monitoring of metabolic changes using wearable technology, continuous glucose monitoring, and ketone measurements, along with blood, saliva, and stool lab tests. The goal is to assess the effects of these interventions on metabolic health and overall well-being, identifying potential trends and correlations throughout the study period.

Treatment: