Monitoring of MDRO Dynamics and Resistance Mechanisms in a University Hospital Network (R-Net)

University of Luebeck

Status: Enrolling

Conditions: MDRO

Treatments: Other: rectal swab

Study type: Observational

Funder types: Other

Identifiers

NCT04937361

DZIF TTU 08.824

Details and patient eligibility

About

Survey on the prevalence of MDRO to monitor the import of MDRO from the community. Rectal swabs will be taken and cultivated. Survey on community-onset and nosocomial bloodstream infections will be documented and strains will be isolated. For each BSI a clinical data set will be obtained (e.g. patient age, gender, date of hospitalization, antibiotic therapy). Genetic analysis of MDRO from the prevalence and BSI study. In a subset of patients the microbiome-resistome interactome will be analysed in more detail. Furthermore, the impact of infection control measures due to the Covid-19 pandemic on nosocomial BSI will be investigated.

Enrollment: 12,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• at least 18 years old
• informed consent
• inpatient

Exclusion criteria

• less than 18 years old
• Not capable of giving informed consent
• outpatient