Monitoring of Systemic or Organ Perfusion for Preterm Infants

Inha University Hospital

Status: Completed

Conditions: Hypotension; Oliguria; Necrotizing Enterocolitis of Newborn; Infant, Premature; Sepsis Newborn; Hypoperfusion in Newborn

Treatments: Device: NIRS (near Infra-red spectroscopy)

Study type: Observational

Funder types: Other

Identifiers

NCT03136172

Neoperfusion-2017

Details and patient eligibility

About

To investigate biomarker reflects systemic or specific organ perfusion well, we are going to the observational comparison study using several hemodynamic monitoring methods in the premature infants. It includes near-infrared spectroscopy (NIRS), pulse oximetry with perfusion index (PI) and pleth variability index (PVI) and functional echocardiography.

Full description

Hemodynamic observational comparisons will be performed in 6 episodes below on each patient.

1. first 24 hours after birth
2. during red blood cell (RBC) transfusion: from 4 hours before to 4 hours after the transfusion
3. suspicion of necrotizing enterocolitis: from the suspicion point for 48 hours
4. suspicion of sepsis: from the suspicion point for 48 hours
5. oligouria (< 1 mL/kg/hour of urine): for 48 hours
6. hypotension (mean blood pressure < 30 mmHg): for 48 hours

Enrollment: 85 patients

Sex: All

Ages: Under 2 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• premature infants with 32 weeks or less of gestational age or 1,500 g or less of birth weight

Exclusion criteria

• infants without the consent of their guardians

Trial design

85 participants in 1 patient group

Premature infant

Description:

premature infants with 32 weeks or less gestational age or 1,500 g or less birth weight, who born in the Inha university hospital and admit to the neonatal intensive care unit of the Inha university hospital

Treatment:

Device: NIRS (near Infra-red spectroscopy)