Monocentric Study on the Use of Teriparatide in Children With hypoparathyroïdism (FOR-HYPO)

Civil Hospices of Lyon

Status: Unknown

Conditions: Hypoparathyroidism

Treatments: Other: Serum calcium concentrations results

Study type: Observational

Funder types: Other

Identifiers

NCT04126941

2019 FOR-HYPO

Details and patient eligibility

About

Pediatric hypoparathyroidism is an orphan disease. Conventional management combines native and active vitamin D, calcium supplementation and sometimes phosphate binders, with the risk of long term hypercalciuria, nephrocalcinosis and further renal impairment. The use of teriparatide has been reported in adults (daily or bi-daily subcutaneous infusions) and in children (rather continuous subcutaneous infusion) as second-line therapy.

The objective of this study is to obtain efficacy and safety data on the use of teriparatide in children with hypoparathyroidism to improve our knowledge of their management.

Enrollment: 9 estimated patients

Sex: All

Ages: 2 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with hypoparathyroidism
• Patients treated with teriparatide
• Patients followed in the reference center for calcium and phosphate metabolism diseases of Lyon.
• For children under 18: patient and parent (s) / parent having been informed of the study and having expressed their non-opposition

Exclusion criteria

• No social security support

Trial design

9 participants in 1 patient group

Teriparatide

Description:

Patients with hypoparathyroidism treated by teriparatide

Treatment:

Other: Serum calcium concentrations results