Monopolar Radiofrequency Versus Pulsed Dye Laser for Treatment of Acne Scars (MRFPDL)

Cairo University (CU)

Status: Completed

Conditions: Acne Atrophica

Treatments: Device: Pulsed dye laser; Device: Monopolar radiofrequency

Study type: Interventional

Funder types: Other

Identifiers

NCT04461366

P.T.REC/012/002410

Details and patient eligibility

About

Background: The acne scar is a common disorder characterized by skin eruption or abnormalities on face, chest, and/or back in the adolescence which affect the cosmetic appearance.

Purpose: The main aim of this study was to investigate whether monopolar radiofrequency (MRF) or pulsed dye laser (PDL) is more effective in the cases suffering from acne scars in the form of reducing acne scars and improving the cosmetic appearance.

Full description

Thirty patients suffering from moderate or severe acne scars were randomly assigned into two equal groups. Group A (MRF group): received 2 sessions per week with MRF for 8 weeks. Group B (PDL group): received 1 session per week with PDL for 8 weeks. The severity of acne scars was assessed before and after treatment by using the clinical evaluation scale for acne scarring (ECCA) scale and the self-assessment of clinical acne-related scars (SCARS) scale. Quality of life and the emotional impact of acne scars were evaluated by the facial acne scar quality of life (FASQoL) scale.

Enrollment: 30 patients

Sex: All

Ages: 19 to 23 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with mild to severe acne scar
• Patients with acne scar in the face

Exclusion criteria

• Smokers and alcohol drinker
• Patients who had a history of diabetes, circulatory or sensory disorders
• Patients who had a history of frequent sunburns
• Patients with nodulocystic acne

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

monopolar radiofrequency (MRF) group

Experimental group

Description:

Monopolar Radiofrequency Diathermy (LVT-250, Korea) was used at average energy160-180 W, main power 50/60 Hz, 40˚C \~ 45˚C Temperature, RF output 470 kHz, 20 mm electrode size.

Treatment:

Device: Monopolar radiofrequency

Pulsed dye laser (PDL) group

Active Comparator group

Description:

Flash lamp pulsed dye laser; Candela SPTL-1 (Candela Corp., Wayland, Mass.) with the following parameters: (585nm wavelength, 450 msec pulse duration, 6.5 to 7.5 J/cm² energy density and 5or 7mm spot size).

Treatment:

Device: Pulsed dye laser