Mood and Subthalamic Nucleus (STN) Deep Brain Stimulation (MOST)

University of Florida

Status: Completed

Conditions: Movement Disorders

Study type: Observational

Funder types: Other

Identifiers

NCT00954772

00056229

Details and patient eligibility

About

The purpose of this research study is to investigate any changes seen in mood or behavior following deep brain stimulation for movement disorders.

Enrollment: 91 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Idiopathic PD diagnosed by a movement disorders neurologist
• Approved by a movement disorders neurologist as clinically needing a DBS device
• Absence of significant cognitive dysfunction (Mattis Dementia Rating Scale Score of greater than or equal to 116)
• MRI without evidence of structural abnormality (stroke, tumor, malformation, etc)
• No prior neurosurgical intervention

Exclusion criteria

• None

Trial design

91 participants in 2 patient groups

Staged Bilateral STN DBS

Simultaneous Bilateral STN DBS