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Morphine-Sparing Effect And Safety Of Parecoxib Administered Intravenously For The Treatment Of Postoperative Pain

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Pfizer

Status and phase

Completed
Phase 3

Conditions

Pain, Postoperative

Treatments

Drug: Parecoxib and placebo

Study type

Interventional

Funder types

Industry

Identifiers

NCT00143169
A3481004

Details and patient eligibility

About

To validate the morphine-sparing effect and safety of parecoxib administered intravenously for the treatment of Chinese subjects with postoperative pain following gynecological or orthopedic surgery.

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Undergo gynecological or orthopedic surgery under epidural anesthesia

Exclusion criteria

  • A previous history of intolerance or hypersensitivity to any NSAID, cyclooxygenase-2 selective inhibitors, sulphonamides, or any of the excipients of parecoxib.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

Trial contacts and locations

8

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Data sourced from clinicaltrials.gov

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