Morphine-Sparing Effect And Safety Of Parecoxib Administered Intravenously For The Treatment Of Postoperative Pain

Pfizer

Status and phase: Completed; Phase 3

Conditions: Pain, Postoperative

Treatments: Drug: Parecoxib and placebo

Study type: Interventional

Funder types: Industry

Identifiers

NCT00143169

A3481004

Details and patient eligibility

About

To validate the morphine-sparing effect and safety of parecoxib administered intravenously for the treatment of Chinese subjects with postoperative pain following gynecological or orthopedic surgery.

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Undergo gynecological or orthopedic surgery under epidural anesthesia

Exclusion criteria

• A previous history of intolerance or hypersensitivity to any NSAID, cyclooxygenase-2 selective inhibitors, sulphonamides, or any of the excipients of parecoxib.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind