Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy

University of Sao Paulo

Status: Completed

Conditions: Dysthyroid Orbitopathy

Study type: Observational

Funder types: Other

Identifiers

NCT00665795

1152/05

Details and patient eligibility

About

The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging.

Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.

Full description

Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging:

Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).

Enrollment: 80 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Graves´Orbitopathy diagnosed based on previously reported criteria
• Age above 20 years
• Good cooperation for performing Visual Field test
• Spherical refraction within ± 5 D and cylinder correction within ± 3 D

Exclusion criteria

• Graves´Orbitopathy not diagnosed

Trial design

80 participants in 2 patient groups

1Patients with Graves´orbitophathy.

Description:

Patients with Graves´orbitophathy.

2 Patients with detected DON

Description:

Patients with Graves´orbitophaty and detected dysthyroid optic neuropathy (DON)