Morton's Neuroma: Manipulation Versus Steroid Injection

Dundee Podiatry Clinic

Status: Completed

Conditions: Morton Neuroma

Treatments: Drug: methylprednisolone; Procedure: manual manipulation

Study type: Interventional

Funder types: Other

Identifiers

NCT05707572

PDN001

129586 (Registry Identifier)

Details and patient eligibility

About

This study compares manipulative therapy to steroid injection in the treatment of Morton's Neuroma.

Full description

The aim of this study is to establish whether manipulative therapy is an effective treatment for Morton's neuroma, a nerve entrapment in the foot. Steroid injection is the current gold standard conservative treatment for this condition. Therefore, a subject group shall be compared to a steroid injection intervention group. Outcomes will be compared using visual analogue pain scales -VAS, Foot Function Index questionnaires and algometric pressure threshold testing. An improvement in the manipulation group VAS of 20mm above the injection group shall be considered as the minimum worthwhile change as this has been identified as the minimum clinically important difference in pain between treatment groups in visual analogue pain scales.

Enrollment: 62 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical diagnosis of morton's neuroma
• over 18 years of age
• presenting VAS score > 30mm

Exclusion criteria

• diabetes,
• rheumatoid arthritis
• fibromyalgia.
• Those currently taking Statins or analgesics
• previous neuroma surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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62 participants in 2 patient groups

steroid injection

Active Comparator group

Description:

1 injection of 1mL methylprednisolone \[40mg\]with 1 mL 2% lignocaine

Treatment:

Drug: methylprednisolone

manual manipulation

Experimental group

Description:

weekly manipulations to the metatarsophalangeal joints of the forefoot for 6 weeks

Treatment:

Procedure: manual manipulation