Motivational Interviewing and Medication Review in Coronary Heart Disease (MIMeRiC)

Göran Petersson

Status: Completed

Conditions: Coronary Heart Disease

Treatments: Behavioral: MI and Medication review; Behavioral: Standard Treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT02102503

GLAS-1-2013

Details and patient eligibility

About

Low medication adherence in patients with coronary heart disease increases mortality.

This study investigates if an intervention of medication review and counselling can improve patients' medication adherence and treatment results.

Full description

The study will investigate the effects of medication review and Motivational Interviewing (MI) on patients with Coronary Heart Disease (CHD). Clinical pharmacists competent in MI and cardiology will conduct medication interviews and medication reviews at the outpatient clinic. The intervention will continue during 9 months, with interviews and reviews as needed.

Follow-up of results will take place 16 months after inclusion (corresponding to 4 months after the end of intervention).

The MI-Component will be quality assured by MITI 4.2-coding (Motivational Interviewing Treatment Integrity). The study will investigate effects on clinical outcomes, medication adherence, patients´ beliefs about medicines and quality of life.

Enrollment: 417 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admitted for angiography
• Verified Coronary Artery Disease (ICD-10 I20-I21)
• Planned for follow up at the out-patient clinic (standard treatment)
• Swedish speaking

Exclusion criteria

• Cognitive impairment or any othe condition making interview or phone calls impossible.
• Non-participation in the standard follow-up
• Prior participation in this study

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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417 participants in 2 patient groups

MI and Medication review

Experimental group

Description:

The intervention starts three months post-discharge after the standard treatment at the out-patients clinic. A medication review focused on cardiovascular drugs, and a counselling session with a clinical pharmacist using Motivational Interviewing (MI)-approach, and a follow-up phone call two weeks later. For patients with negative beliefs about medicines, three additional MI-sessions in clinic or by phone are planned together with the patient. Irrespective of beliefs the intervention ends with a second medication review and counselling session, which is coordinated with the 12-months post-discharge follow-up in primary care.

Treatment:

Behavioral: MI and Medication review

Behavioral: Standard Treatment

Standard treatment

Active Comparator group

Description:

Standard treatment at the cardiology out-patient clinic. Follow-up by nurse after two weeks and by physician after two months.

Treatment:

Behavioral: Standard Treatment