Motor and Cognitive Functions in Acquired and Developmental Brain Damaged Patients

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status: Unknown

Conditions: Perceptual Disorders; Cerebral Palsy; Hemiparesis

Treatments: Behavioral: Motor, cognitive and neuropsychological assessment

Study type: Interventional

Funder types: Other

Identifiers

NCT02543424

2015/10FEV/053

Details and patient eligibility

About

Neurological pathologies cause important and permanent disabilities in every day life. These pathologies can follow stoke, affecting two people per one thousand each year or cerebral palsy, affecting two births per one thousand each year. To date, the diagnosis and the rehabilitation of motor and cognitive problems has been carried out separately by different domains. For example, physiotherapists have focused on motor problems and neuropsychologists have focused on cognitive functions. However, a number of studies have demonstrated a link between motor and cognitive abilities in adults and children. The present study has three main aims: (1) to better evaluate motor and cognitive problems in brain damaged patients (all ages), (2) to understand the link between motor and cognitive abilities in patients and healthy participants and, (3) to propose new types of therapies based on the link between motor and cognitive functions.

Enrollment: 400 estimated patients

Sex: All

Ages: 5+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Congenital cerebral palsy and acquired brain injury children and adult patients
• Presenting upper limb paresis and/or hemineglect
• Between the age of 3 to 90.
• Able to understand and carry out simple verbal instruction

Exclusion criteria

• IQ < 70
• Severe aphasia, attentional disorder or psychiatric disorders
• Neurodegenerative disorders

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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400 participants in 2 patient groups

Patient group

Experimental group

Description:

Brain damaged adults with either hemiparesis and/or hemineglect. Brain damaged children with developmental and/or acquired disease inducing hemiparesis and/or hemineglect.

Treatment:

Behavioral: Motor, cognitive and neuropsychological assessment

Control group

Sham Comparator group

Description:

Healthy adults and children.

Treatment:

Behavioral: Motor, cognitive and neuropsychological assessment