Motor Imagery and Action Observation for Gait Function in MS

Hacettepe University

Status: Not yet enrolling

Conditions: Multiple Sclerosis

Treatments: Behavioral: Nature Video; Behavioral: Action Observation + Motor Imagery

Study type: Interventional

Funder types: Other

Identifiers

NCT07137624

FTREK25/48

Details and patient eligibility

About

This study will investigate whether mentally simulating walking movements while watching others walk can improve walking performance in individuals with Multiple Sclerosis (MS). Participants will be divided into two groups: one group will watch walking videos and imagine themselves walking, while the other group will watch nature scenes. The study will measure muscle activity and walking patterns to assess the effects. The results may help support the use of mental practice techniques to improve mobility in people with MS.

Full description

This study aims to explore the impact of mental simulation of walking movements on walking performance in individuals with Multiple Sclerosis (MS). The participants will be randomly assigned to two groups: the experimental group will watch walking-related videos and engage in mental imagery exercises, imagining themselves walking, while the control group will watch nature scenes without any walking-related content.

Objectives:

To determine whether mental imagery can enhance walking ability and gait parameters in individuals with MS.

To measure the effect of mental simulation on muscle activity and walking patterns, including stride length, walking speed, and balance.

Study Procedure:

The study will consist of multiple sessions, where participants will first undergo baseline assessments of walking ability. Following this, they will engage in either the walking video and imagery task (experimental group) or the nature video viewing task (control group) for a predetermined period of time. Measurements of muscle activity using electromyography (EMG) and walking patterns will be recorded before and after the intervention.

Potential Impact:

The results from this study may provide insights into the use of mental practice techniques as a non-invasive intervention to improve mobility in individuals with MS, a population often affected by walking difficulties. Mental imagery could serve as an adjunct therapy to traditional physical rehabilitation methods.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A confirmed diagnosis of multiple sclerosis (MS) by a neurologist
• No history of relapse within the past 3 months and not currently experiencing a relapse
• A score of 24 or higher on the standardized Mini Mental State Examination

Exclusion criteria

• Presence of serious health conditions affecting the muscles, heart, lungs, or metabolism that could interfere with participation
• History of other neurological disorders, head injury, or chronic psychiatric conditions
• Chronic pain lasting longer than six months
• Significant muscle stiffness in the legs that may affect EMG recordings
• Hearing difficulties
• Vision problems as determined by the Snellen visual acuity test

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Arm 1

Experimental group

Description:

Arm 1: Experimental Group: Action Observation + Motor Imagery

Treatment:

Behavioral: Action Observation + Motor Imagery

Arm 2

Other group

Description:

Arm 2: Control Group: Nature video

Treatment:

Behavioral: Nature Video