ClinicalTrials.Veeva

Menu

Motor Learning in Knee Osteoarthritis (MLKOA)

S

St. Pölten University of Applied Sciences

Status

Unknown

Conditions

Lower Extremity Biomechanics
Physiotherapy
Knee Osteoarthritis

Treatments

Other: External Focus Of Attention
Other: Internal Focus Of Attention

Study type

Interventional

Funder types

Other

Identifiers

NCT04445350
StPoltenUAS

Details and patient eligibility

About

Non-surgical treatment options, like exercise therapy, show excellent short-term effects regarding pain reduction and improvement of knee function. However, mid- and long-term effects are missing so far. This might indicate that long-lasting changes in motor-skill performance (Motor Learning) have not occurred. Motor learning is associated with permanent changes in the capability for skilled movement behavior avoiding unfavorable joint loads and inappropriate muscle activation patterns, leading to compensatory movement strategies. One-sided and high repetitive loads in the knee joint could be one reason for the progression of knee osteoarthritis. Physiotherapeutic strategies should therefore be able to stimulate motor learning processes. In physiotherapy, motor learning can be optimized by using instructions and feedback, targeting an external focus of attention, when learning specific movement patterns. This study investigates the effects of a 12 week exercise therapy program, using an external focus of attention, on functional and biomechanical parameters in patients with knee osteoarthritis. To measure possible changes, functional measurements are taking place at baseline, after 6, 12 and 24 weeks. The biomechanical measurements (3D gait analysis) are taking place at baseline, after 12 and 24 weeks.

Enrollment

50 estimated patients

Sex

All

Ages

45 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Kellgren-Lawrence-Score 1-3
  • BMI < 33
  • Free range of motion in the knee joint

Exclusion criteria

  • Activated knee osteoarthritis
  • Lower extremity surgery in the past 6 weeks
  • Intake or injection of corticosteroids in the past 3 month
  • Long-term medication non-steroidal anti-inflammatory drugs
  • Neurological diseases
  • Drug or alcohol abuse

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

50 participants in 2 patient groups

External focus of attention training program
Experimental group
Description:
The intervention group receives a strength and neuromuscular training program. The training instructions have an external focus of attention.
Treatment:
Other: External Focus Of Attention
Internal focus of attention training program
Active Comparator group
Description:
The control group receives a strength and neuromuscular training program. The training instructions have an internal focus of attention.
Treatment:
Other: Internal Focus Of Attention

Trial contacts and locations

1

Loading...

Central trial contact

Barbara Wondrasch, PhD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems