Motor Performance in Parkinson's Disease After High Intensive Exercise or Deep Brain Stimulation

University of Copenhagen

Status: Completed

Conditions: Parkinson's Disease

Treatments: Other: High intensive antigravity locomotor exercise; Procedure: Deep Brain Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT01446549

H-3-2010-051

Details and patient eligibility

About

The purpose of this study is (1) to provide quantitative information of the motor manifestations of Parkinson's disease and (2) to quantify the effect of high intensive antigravity locomotor exercise or Deep Brain Stimulation implantations in Parkinson's disease.

Enrollment: 40 patients

Sex: Male

Ages: 50 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria (exercise arm):

• Idiopathic Parkinson's disease
• A stable condition the last 6 months
• Hoehn and Yahr 2 - 3

Inclusion Criteria (Deep Brain Stimulation arm):

• Patients referred to Deep Brain Stimulation

Exclusion Criteria:

• Cardiovascular disease
• Conditions that contraindicate physical exercise or the examination

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Deep Brain Stimulation

Experimental group

Treatment:

Procedure: Deep Brain Stimulation

Locomotor Exercise

Experimental group

Treatment:

Other: High intensive antigravity locomotor exercise