Motor Signature, Falls Risk, and Home-Based Interventions in Older Adults With Mild Cognitive Impairment

Taipei Medical University

Status: Unknown

Conditions: Mild Cognitive Impairment; Fall

Treatments: Behavioral: Computerized training; Behavioral: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03839576

MOST106-2314-B-038-046

Details and patient eligibility

About

A single-blinded, randomized controlled trial is designed to compare the effects of social interaction, computerized cognitive training, lower extremity strengthening, and tai chi chuan on improving cognitive functions and gait/mobility and reducing falls among 228 subjects with mild cognitive impairment, in which the influence of adherence to the intervention programs will also be examined.

Enrollment: 252 estimated patients

Sex: All

Ages: 65 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least 65 years old
• Had a fall at least 3 months prior to the baseline assessment
• Can ambulate independently
• Has mild cognitive impairment

Exclusion criteria

• Cannot ambulate independently and communicate with researchers
• Have a major unstable cardiopulmonary disease (e.g., ischemic chest pain, shortness of breath, recurrent syncopal episodes, orthopnea, paroxysmal nocturnal dyspnea, palpitations, or tachycardia)
• Have a contraindication to physical exercise (e.g., severe osteoarthritis or severe pulmonary hypertension)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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252 participants in 4 patient groups

Computerized cognitive training

Experimental group

Description:

The computerized cognitive training will take place at each participant's residence. Participants will be asked to practice at least 1 session a day for 6 months, and a session lasts for 60 minutes.

Treatment:

Behavioral: Computerized training

Lower extremity strengthening

Experimental group

Description:

This exercise will comprise stretching, muscle strengthening, and balance training at increasing difficulty levels, tailored and supervised by a physical therapist, and will take place at a subject's residence or in the neighborhood once a week for 6 months. Each session will last 60 min.

Treatment:

Behavioral: Exercise

Tai chi chuan

Experimental group

Description:

The 8-form Yang-style tai chi intervention will take place at a subject's residence or the neighborhood once a week for 6 months, and each session will last for 60 minutes.

Treatment:

Behavioral: Exercise

Social interaction

No Intervention group

Description:

Immediately after the baseline assessment, the care manager will visit the subject in this group once for comparability with the other two intervention groups.