Mouth Dissolving Mosapride Tables Enhance Post Cesarean Gut Recovery

Benha University

Status and phase: Completed; Phase 3

Conditions: Prevention of Postoperative Ileus

Treatments: Drug: Mosapride; Drug: Placebo Oral Tablet

Study type: Interventional

Funder types: Other

Identifiers

NCT03477266

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Details and patient eligibility

About

Giving women one day before and immediately after cesarean section a mouthly dissolving mosapride tablets 2every every 8 hours for maximum of 5 days ,or getting recovered gastrointestinal functions And assess preoperative gastrointestinal functions

Full description

Uncomplicated post cesarean women one day before and immediately after elective cesarean receive 2 mouthly dissolving mosapride tablets every 8 hours maximum for 5 days and clinical care giver follow the woman's gastrointestinal functions, including intraoperative and postoperative nausea vomiting, passing flatus, hearing intestinal sounds, passing stools, occurring of paralytic ileus, length of the hospital stay

Enrollment: 400 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all women undergoing elective cesarean section

Exclusion criteria

• prior abdominal surgery, abdominal adhesion, chronic constipation, allergy to mosapride

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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400 participants in 2 patient groups, including a placebo group

Mouth dissolving mosapride

Experimental group

Description:

Fluxopride 5mg of Macryrl egypt 2 tablets one day before and immediately after elective cesarean section every 8hour for maximum of 5 days

Treatment:

Drug: Mosapride

Placebo mouth dissolving tablets

Placebo Comparator group

Description:

Dummy identical tablets taken in the same way

Treatment:

Drug: Placebo Oral Tablet