Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children

Universidade Estadual da Paraiba

Status: Completed

Conditions: Gingivitis

Treatments: Drug: Punica granatum Linn.; Drug: chlorhexidine

Study type: Interventional

Funder types: Other

Identifiers

NCT02949583

Effectiveness of Pomegranate

Details and patient eligibility

About

The mechanical control of supragingival biofilm is accepted as one of the most important measures to prevent dental caries and periodontal diseases. Nevertheless, maintaining dental surfaces biofilm-free is not an easy task. In this regard, numerous studies researches have demonstrated the effectiveness of mouthwashes containing antimicrobial active ingredients that prevent and control both supragingival biofilm and gingivitis, specially when used adjunctively to mechanical oral hygiene regimens.

Full description

In vitro and clinical researches using Punica granatum Linn shows antimicrobial and antiadherent activity against dental biofilm microorganisms. The purpose of this study was to evaluate the clinical effectiveness of a mouthwash of Punica granatum Linn. against biofilm and gingival inflammation in school children

Enrollment: 35 patients

Sex: All

Ages: 9 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age group: 09-12 years old
• Presence of at least 20 teeth
• Simplified Oral Hygiene Index (S-OHI)≥ 1,6

Exclusion criteria

• Use of orthodontic appliance
• Recent (in the past 2 months)use of antibiotics and mouthwashes

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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35 participants in 2 patient groups

Punica granatum Linn.

Experimental group

Description:

The childrens used the mouthwash contain pomegranate 6,25% twice daily for 14 days.

Treatment:

Drug: Punica granatum Linn.

chlorhexidine

Active Comparator group

Description:

The childrens used the mouthwash contain chlorhexidine 0.12% twice daily for 14 days.

Treatment:

Drug: chlorhexidine