Move for Your Mind - Pilot Trial (MFYM - P)

University of Zurich (UZH)

Status: Completed

Conditions: Mild Dementia; Mild Cognitive Impairment; Fall Prevention

Treatments: Other: Jaques-Dalcroze eurhythmics; Drug: Vi-De 3; Other: Home exercise program

Study type: Interventional

Funder types: Other

Identifiers

NCT02279316

SNCTP000000580

Details and patient eligibility

About

Move for your mind is a single blind, 3-arm randomized controlled clinical pilot trial. The study aims to test the effect of a weekly Dalcroze eurhythmics program (arm 1) and a home strength exercise program (arm 2) against control (no exercise) on the rate of falling, quality of life, gait performance and cognitive function. All groups receive vitamin D. In addition the study shall test the feasibility of the recruitment and the interventions in this target population.

The study includes 60 seniors, age 65 and older, with mild cognitive impairment or mild dementia. Participants are recruited by the memory clinic of City Hospital Waid.

During the 12 months follow-up, participants will have 3 clinical visits (baseline, 6 and 12 month). Despite major efforts the target population is very difficult to recruit and adherence to treatment is low. We therefore decided to stop recruitment and to use this trial as a pilot trial for future clinical trials of the same topic.

Full description

Primary objective To test whether the Jaques-Dalcroze eurhythmics program (1 hour a week for 12 months) and/or the simple home exercise program (3 × 30 min a week for 12 months) will decrease rate of falls in seniors with MCI or mild dementia compared with the control group.

Secondary objectives Objective 1: To test whether the Jaques-Dalcroze eurhythmics program (1 hour a week for 12 months) and/or the simple home exercise program (3 × 30 min a week for 12 months) decreases 12-month risk of falling at least once in seniors with MCI or mild dementia compared with the control group.

Objective 2: To test whether the Jaques-Dalcroze eurhythmics program (1 hour a week for 12 months) and/or the simple home exercise program (3 × 30 min a week for 12 months) improves cognitive func-tion and alertness in seniors with MCI or mild dementia compared with the control group.

Objective 3: To test whether the Jaques-Dalcroze eurhythmics program (1 hour a week for 12 months) and/or the simple home exercise program (3 × 30 min a week for 12 months) decreases gait variability in seniors with MCI or mild dementia compared with the control group.

Objective 4: To test whether the Jaques-Dalcroze eurhythmics program (1 hour a week for 12 months) and/or the simple home exercise program (3 × 30 min a week for 12 months) improves quality of life in seniors with MCI or mild dementia compared with the control group.

Enrollment: 19 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 65+ years
• Diagnosed with MCI or mild dementia by the memory clinic of City Hospital Waid

Exclusion criteria

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

19 participants in 3 patient groups

Jaques-Dalcroze eurhythmics

Experimental group

Description:

Jaques-Dalcroze eurhythmics (60min/wk) + 800 IU Vitamin D3

Treatment:

Drug: Vi-De 3

Other: Jaques-Dalcroze eurhythmics

Home exercise program

Experimental group

Description:

Home exercise strength program (3x30min/wk) + 800 IU vitamin D

Treatment:

Other: Home exercise program

Drug: Vi-De 3

Vitamin D only

Other group

Description:

800 IU Vi-De 3

Treatment:

Drug: Vi-De 3