MOVE Protocol - Movement-Oriented Velocity of Engagement

MMSx Authority Institute for Movement Mechanics and Biomechanics Research Inc

Status: Completed

Conditions: Musculoskeletal Pain - Acute and Subacute Conditions

Treatments: Behavioral: MOVE Rehabilitation Protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT07220200

MOVE-001/2025

Details and patient eligibility

About

A Prospective, Multi-Site, Interventional Case-Series Evaluating the MOVE (Movement-Oriented Velocity of Engagement) Protocol for Musculoskeletal Pain Recovery

Full description

The MOVE Protocol is a structured, biomechanics-based rehabilitation framework designed to accelerate recovery from musculoskeletal pain conditions through progressive mobilization and neuromuscular control. This interventional case-series involved multiple clinical and training centers (BodyGNTX, GFFI, IIKBS, ASFU) and applied standardized MOVE sessions under the supervision of certified movement specialists. Assessments included pain scoring (NRS), functional mobility (LEFS/UEFI), and balance control, measured at baseline, week 2, week 4, and week 8. The protocol followed ICH-GCP E6(R2) and Helsinki 2013 guidelines, with institutional ethics approval from MMSx Authority IREB. The study demonstrated safe and effective early-movement outcomes across diverse populations, emphasizing mobility, load optimization, and neuromuscular revalidation.

Enrollment: 40 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Adults aged 18-65 years diagnosed with acute or subacute musculoskeletal pain or movement restriction (≤12 weeks duration).

  • Capable of performing supervised rehabilitation and daily movement tasks.
  • Able to provide informed consent and comply with study assessments.
  • Baseline pain score ≥4 on the Numerical Rating Scale (NRS).

Exclusion criteria

• Chronic pain (>12 weeks) or neurological disorders affecting movement control.

  • Post-surgical cases or fractures within the past 3 months.
  • Cardiopulmonary or systemic illness contraindicating exercise participation.
  • Pregnancy or conditions limiting safe participation in physical rehabilitation.
  • Refusal to sign informed consent.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Move Protocol

Experimental group

Description:

Participants received the MOVE (Movement-Oriented Velocity of Engagement) rehabilitation protocol, consisting of four progressive phases: Mobilize, Optimize Load, Validate Neural Control, and Energize Recovery. The program emphasized functional movement restoration, load tolerance, and neuromuscular coordination.

Treatment:

Behavioral: MOVE Rehabilitation Protocol