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Movement Dynamics of Knee Osteoarthritis and Total Knee Replacement (MDOA&TKR)

U

University of Portsmouth

Status

Enrolling

Conditions

Knee Osteoarthritis
Total Knee Replacement

Treatments

Other: No intervention

Study type

Observational

Funder types

Other

Identifiers

NCT06829433
SHFEC 2024-007

Details and patient eligibility

About

This research aims to explore differences in walking and functional movement mechanics, exercise response, and physical activity between people with osteoarthritis (OA), those who have undergone total joint replacement, and healthy individuals.

Full description

People living with OA tend to be less physically active than those without the disease, which is often due to pain, stiffness and joint instability. This reduction in physical activity can lead to additional health problems down the line. When the disease becomes severe, joint replacement surgeries are sometimes performed to relieve pain and improve individuals' quality of life. However, despite reducing pain, there is little evidence to show that joint replacement surgeries encourage individuals to return to healthy physical activity levels.

Reasons for the lack of change may include a failure to address unhealthy walking and movement patterns which could still be causing pain and instability and reduced physical fitness levels.

By investigating these reasons, we hope that findings from this study will help to inform future interventions that improve clinical outcomes and quality of life for individuals with OA and post-joint replacement.

Enrollment

36 estimated patients

Sex

All

Ages

40 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Diagnosed symptomatic bilateral or unilateral knee osteoarthritis, self-reported ability to walk without an aid for 10 minutes and to ascend and descend stairs, no neurological conditions or other musculoskeletal pathology/injury which would impact walking gait.

Exclusion criteria

  • Unable to walk at 0.8 m/s, exclusion based on IMO screening, non-English speaking, lacking ability to consent.

Trial design

36 participants in 3 patient groups

Total Knee Replacement
Treatment:
Other: No intervention
Knee Osteoarthritis
Treatment:
Other: No intervention
Asymptomatic Controls
Treatment:
Other: No intervention

Trial contacts and locations

1

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Central trial contact

Josie Morris, BSc; Joseph Moore, PhD

Data sourced from clinicaltrials.gov

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