MR Characterisation/Localisation of Breast Cancer

Institute of Cancer Research, United Kingdom

Status: Completed

Conditions: Breast Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01567137

CCR 2995 07/H0806/85

Details and patient eligibility

About

Objective: To determine the accuracy of multi-functional magnetic resonance (MR) in detecting, localising and characterising satellite lesions in relation to an index breast tumour in order to improve definition of clinical target volume after local excision.

Hypothesis: Pre-operative multi-functional MR has high sensitivity and specificity for localising unsuspected multifocal and multicentric lesions in women diagnosed with early breast cancer.

Enrollment: 16 patients

Sex: Female

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Biopsy proven invasive ductal carcinoma of the breast
• Unifocal disease
• Patient proceeding to mastectomy

Exclusion criteria

• Multifocal disease
• Previous surgery to ipsilateral breast
• Neoadjuvant chemotherapy
• Ferromagnetic implants
• Claustrophobia
• Cup size DD or greater