MR Compatible Accelerometer for Respiratory MOTion Measurement (MARMOT)

Central Hospital, Nancy, France

Status: Completed

Conditions: Heart Disease

Treatments: Device: MRI compatible motion sensor (MARMOT)

Study type: Interventional

Funder types: Other

Identifiers

NCT02894632

2012-A00874-39

Details and patient eligibility

About

A novel magnetic resonance (MR) compatible accelerometer for respiratory motion sensing (MARMOT) has been developed as a surrogate of the vendors' pneumatic belts. The aim is to model and correct respiratory motion for free-breathing thoracic-abdominal MR imaging and to simplify patient installation.

Full description

Respiratory motion is a serious problem in the acquisition of high-quality thoracic/abdominal magnetic resonance (MR) images. Various methods have been proposed to compensate the motion-induced artefacts, including breathholding, respiratory gating and model-driven motion correction.

Breath-holding is the simplest among the three. However this conventional clinical method induces various problem, including inefficient use of scanners, inconsistent organ position between each breath-hold, imaging an altered physiological status and patient inconvenience especially for those who suffer from respiration difficulties. Free-breathing MR acquisition has therefore become of great clinical interest recently.

The investigators intend to examine the efficacy of the MARMOT sensors for:

• modelling and predicting the respiratory motions in abdominal scans,
• correcting for the respiratory motion in a cardiac cine scan, via a reconstruction-based method.

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• To not have cardiac, hepatic or renal pathology
• To be more than 18
• To be enrolled in a social security plan
• To have signed an informed consent
• To have preliminary medical examination

Exclusion criteria

• Contraindication: implantable devices (pacemakers, defibrillators, cochlear implants, etc.), metallic foreign bodies
• Impossibility to undergo MRI : claustrophobia, morbid obesity
• Pregnancy or risk of pregnancy
• Patient under a measure of legal protection

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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24 participants in 1 patient group

Healthy volunteers

Experimental group

Description:

Volunteers without cardiac, hepatic or renal pathology

Treatment:

Device: MRI compatible motion sensor (MARMOT)