MR-Guided Cryoablation of Prostate Bed Recurrences

Mayo Clinic

Status: Active, not recruiting

Conditions: Prostate Tumors

Treatments: Procedure: MR-guided cryoablation

Study type: Interventional

Funder types: Other

Identifiers

NCT01727284

12-002245

NCI-2023-01699 (Registry Identifier)

Details and patient eligibility

About

The purpose of this research is to see if MR-guided cryoablation can effectively treat prostate tumor recurrences.

Enrollment: 107 patients

Sex: Male

Ages: 30 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with "biopsy proven" soft tissue tumor recurrences of prostate fossa
• Surgery is not a desirable alternative therapy at the time of enrollment
• Radiation therapy has failed or not indicated or can be safely postponed
• Tumor size is < 5 cm at its largest diameter
• Tumor does not encompass the rectal wall or external urethral sphincter
• Patient is able to undergo MRI

Exclusion criteria

• N/A

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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107 participants in 1 patient group

MR-guided cryoablation (freezing of tissue and/or tumors)

Experimental group

Description:

Patients undergo cryoablation using the Galil MR-compatible cryoablation system and MRI while on study.

Treatment:

Procedure: MR-guided cryoablation