MRI 3D UTE Hyper-Cones & ZTE for PET/MR Lung Attenuation Correction & for Lung Diagnostic Imaging

University of Zurich (UZH)

Status: Terminated

Conditions: Lung Diseases

Treatments: Diagnostic Test: PET/MR image acquisition

Study type: Interventional

Funder types: Other

Identifiers

NCT03562806

2017-00899

Details and patient eligibility

About

MRI 3D UTE Hyper-Cones & ZTE for PET/MR lung attenuation correction & for lung diagnostic imaging

Full description

The primary objective is to clinically test the feasibility of 3D UTE Hyper-Cones & ZTE in capturing lung density of patients with lung diseases at reasonable clinical imaging times compared to standard MR lung protocols (LAVA-Flex, PROPELLER). Secondly, we want to investigate if Hyper-Cones & ZTE can be used for lung imaging such as vessels and air-pathways, oncological patients, lung nodules and lung infiltration & parenchyma pathophysiology such as chronic obstructive pulmonary disease.

Enrollment: 9 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• informed consent and signature
• clinical PET/CT planned and performed at Wagi site in Schlieren
• male or female patients
• from 18 to 80 years of age.

Exclusion criteria

• same exclusion criteria as for the clinical PET/CT exam (i.e. pregnant women).

Additional exclusion criteria:

• standard exclusion criteria for clinical MRI (evaluated by clinical standard determined by MRI questionnaire).

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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9 participants in 1 patient group

PET/MR (single arm)

Experimental group

Description:

PET and MR sequence acquisition on SIGNA PET/MR device

Treatment:

Diagnostic Test: PET/MR image acquisition