MRI Assessment of Patient Suitability for Cardiac Resynchronization Therapy (CRT)

NYU Langone Health

Status

Suspended

Conditions

Magnetic Resonance Imaging (MRI)

Cardiac Resynchronization Therapy

Treatments

Procedure: Cardiac MRI

Study type

Interventional

Funder types

Other

Identifiers

NCT02728336

14-01686

Details and patient eligibility

About

The goals of this project are to: 1) explore the potential use of magnetic resonance imaging (MRI) data for improved prediction of response to cardiac resynchronization (CRT), and 2) use the MRI-derived data together with a computer model of the cardiovascular system to study the relative roles of different factors in the mechanical effects of dyssynchrony in failure, and in the response (or lack thereof) to CRT.

Enrollment

110 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Male and female patients ages 18 and over scheduled by conventional criteria (symptomatic impairment of cardiac function with broadened QRS) for clinical CRT procedures at NYULMC.
Normal kidney function as determined by GFR levels.

Inclusion Criteria for Controls

Normal kidney function as determined by GFR levels
No significant cardiovascular disease or risk factors.

Exclusion criteria

electrical implants such as cardiac pacemakers or perfusion pumps
ferromagnetic implants such as aneurysm clips, surgical clips, prostheses, artificial hearts, valves with steel parts, metal fragments, shrapnel, tattoos near the eye, or steel implants
ferromagnetic objects such as jewelry or metal clips in clothing (which will be removed)
pre-existing medical conditions including a likelihood of developing seizures or claustrophobic reactions, and any greater than normal potential for cardiac arrest.