MRI of Infrapatellar Fat Pad in Osteoarthritis (IPFP-MRI)

Central South University

Status: Completed

Conditions: Osteoarthritis

Treatments: Radiation: Magnetic resonance imaging

Study type: Observational

Funder types: Other

Identifiers

NCT02829463

JY201507

Details and patient eligibility

About

In this study, the investigators use the clinical documentation and imaging data of MRI to do research. Clinical subjects were divided into two groups: osteoarthritis patients and healthy controls without osteoarthritis. Differences of MRI data were studied between two groups.

Full description

In this study, the investigators applied high precision MRI technique (with as less as a slice thickness of 0.35 mm and without inter-slice gap), and calculated not only the IPFP maximal sagittal area and IPFP volume, but also the quantitated signal, and compared the differences between healthy controls and osteoarthritis patients. This is an observational cross-sectional study without specific interventions to the subjects. MRI is a regular examination in our hospital. And all subjects are included for the reasons of osteoarthritis (need MRI) and healthy controls (pain but not osteoarthritis, also need MRI). The investigator does not assign specific interventions to the subjects of the study.

Enrollment: 121 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with clinical knee osteoarthritis;
• The healthy controls who require MRI test.

Exclusion criteria

• Contraindications to magnetic resonance imaging;
• Rheumatoid arthritis patients;
• Gout;
• Hemophilic arthritis;
• Subjects who take non-steroidal anti-inflammatory drugs (NSAIDs);
• Subjects who take lipid-lowering agents;
• Subjects who have the history of knee trauma;
• Subjects who have the history of knee operation;
• Subjects who have the disease of musculoskeletal tumor near knee;
• Subjects who have joint loose bodies.

Trial design

121 participants in 2 patient groups

osteoarthritis patients

Description:

3.0 Tesla Magnetic resonance imaging was analyzed. It's the documentation from the outpatients and inpatients with osteoarthritis. It's not the intervention the study applied, but the subjects' disease demands.

Treatment:

Radiation: Magnetic resonance imaging

healthy controls

Description:

3.0 Tesla Magnetic resonance imaging was analyzed. It's the documentation from the outpatients and inpatients without osteoarthritis. It's not the intervention the study applied, but the subjects' non-osteoarthritis knee symptom demands.

Treatment:

Radiation: Magnetic resonance imaging