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About
This project is structured around a central study called "Study of genetic factors involved in autism and related conditions ("Genes and Autism" study, sponsor: INSERM). This study explores clinical and genetic aspects of ASD (autism spectrum disorders) and is complemented with several ancillary studies (such as this one) which will use the data of the main study and will allow an extensive review of phenotypes associated with ASD.
In this ancillary study, we will go on the acquisition of anatomical, diffusion and functional MRI in subjects with ASD, relatives and controls. Our group has already performed several neuroanatomical studies of ASD. IWe recruited since 2010 more than 600 subjects (proponents, relatives and controls) to better understand the implication of brain abnormalities in ASD.
This study involves specialized teams in neuroiamging based at INSERM, NeuroSpin (CEA), Robert Debré Hospital (APHP) and Pasteur Institute
Our main objective is to identify structural, connectivity and functional peculiarities in subjects with ASD
Secondary objectives include:
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for patients:
for relatives
for controls
Non-inclusion criteria:
for all subjects
for the relatives
*discovery of non filiation during the genetic analyses
for controls
Exclusion criteria
1,000 participants in 3 patient groups
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Central trial contact
Richard Delorme, M.D, Ph.D; Josselin Houenou, M.D, Ph.D
Data sourced from clinicaltrials.gov
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