MRSA Colonization in Peripartum Women and Their Offspring

Orlando Regional Medical Center

Status: Completed

Conditions: Bacterial Colonization; Pregnancy

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00336427

ORMC-MRSA-Pregnancy

Details and patient eligibility

About

We hypothesize that pregnant women are at baseline risk for carrying community-acquired MRSA, but also have frequent contact with healthcare workers which may put them at risk for hospital-acquired MRSA carriage. Our study aimed to identify the colonization rate of women in active labor and whether transmission to infants may occur.

Full description

Mothers are at risk for carrying MRSA. What this risk is is not known. We have seen a dramatic increase in neonatal intensive care unit MRSA infections. Could mothers transmit MRSA to their newborns if they are asymptomatic carriers? Mothers come into close contact with health care providers, often have other children in daycare (known risk factor) and may have other exposures to MRSA. Our study was designed to sample 300 mother-infant pairs to determine whether MRSA carriage is present in asymptomatic women. The study consisted of obtaining informed consent, then performing a sterile swab of mothers' nares and vaginal area, then babies' nares and umbilicus once the baby was born.

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Singleton pregnancy expected to deliver next 24 hours

Exclusion criteria

• Cesarean sections