MS Versus NICE for Colorectal Lesions

Lyell McEwin Hospital

Status: Completed

Conditions: Colorectal Polyp; Colorectal Neoplasms

Treatments: Other: Modified Sano's classification; Other: NICE classification

Study type: Interventional

Funder types: Other

Identifiers

NCT02963207

2008128

Details and patient eligibility

About

OBJECTIVE: Our study aimed to compare a recently-developed endoscopic classification with an established one for colorectal lesions in a randomised trial between 2013 and 2015.

Full description

OBJECTIVE: Current practice requires histopathological assessment to confirm diagnosis for colorectal lesions detected at colonoscopy. Advances in endoscopic imaging contribute for real-time diagnosis which, apart from being cost and time-saving, also guides decision-making and reduces risks. Our study aimed to compare a recently-developed endoscopic classification with an established one.

DESIGN: The modified Sano's classification (MS) was compared to the Narrow Band Imaging (NBI) International Colorectal Endoscopic classification (NICE) in a randomised trial between 2013 and 2015. An experimented endoscopist classified each polyp, what was compared to histopathology.

Enrollment: 348 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients admitted in the Endoscopy Unit for a colonoscopy
• Patients over 18 years-old
• Patients or their caregivers that have understanding of the procedure and that have signed the consent form for the study

Exclusion criteria

• Patients without colorectal polyps
• Patients with poor bowel preparation
• Patients that do not agree with or withdraw the consent form

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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348 participants in 2 patient groups

Modified Sano's Classification

Experimental group

Description:

Modified Sano's Classification as described by Singh et al. 2013

Treatment:

Other: Modified Sano's classification

NICE classification

Active Comparator group

Description:

NBI International Colorectal Endoscopic Classification as described by Hewett et al. 2012

Treatment:

Other: NICE classification