Mucociliary Clearance Techniques for Acute Bronchiolitis (CLEARBRONCH)

Universidad de León

Status: Not yet enrolling

Conditions: Bronchiolitis Acute; Acute Bronchiolitis Due to Respiratory Syncytial Virus; Bronchiolitis Acute Viral

Treatments: Procedure: Respiratory Physiotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT06689631

ULE

ETICA-ULE-062-2023

Details and patient eligibility

About

To assess the efficacy of mucociliary clearance techniques in non-hospitalised infants with a first episode of mild to moderate acute bronchiolitis.

Enrollment: 70 estimated patients

Sex: All

Ages: 28 days to 12 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Medical diagnosis of first episode of acute Bronchiolitis.
• Acute Bronchiolitis with mild (ESBA score = 1-4) or moderate (ESBA score =5-9) severity according to the ESBA.
• Informed consent signed by parents or legal guardians.

Exclusion criteria

• Infants previously diagnosed with chronic respiratory disease.
• Previous episodes of wheezing.
• Presence of any type of contraindication to receive Respiratory Physiotherapy treatment.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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70 participants in 1 patient group

Treatment group

Experimental group

Description:

The intervention consisted of a Respiratory Physiotherapy session including: mucociliary clearance techniques (prolonged slow expiration and provoked cough), bronchodilator when prescribed and nebulisation with 3% hypertonic saline.

Treatment:

Procedure: Respiratory Physiotherapy