Mucoderm or Connective Tissue Graft for Treatment of Gingival Recessions

University of Sao Paulo

Status: Unknown

Conditions: Gingival Recession

Treatments: Procedure: Root coverage with collagen matrix graft; Other: Basic periodontal treatment; Procedure: Root coverage with subepithelial connective tissue graft

Study type: Interventional

Funder types: Other

Identifiers

NCT03675334

CAAE 58534216.5.0000.5419

Details and patient eligibility

About

Coronally advanced flap plus connective tissue graft (CTG) is the gold standard therapy for root coverage. The bioabsorbable porcine collagen matrix (CM) has been widely used in periodontal and mucogingival surgery as a substitute for CTG and has achieved similar results. The CM has the advantage of no need of a second surgical area and availability overcoming the limitations of donor site in autograft.

The aim of this study is to investigate the use of Mucoderm® in root coverage procedures combined with extended coronally positioned flap (ECAF), test group (TG), in comparison to the connective tissue graft associated with the ECAF, control group (CG).

Enrollment: 18 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• CEJ without significant damage;
• localized bilateral RT1 gingival recession ≥3 mm in the same arch

Exclusion criteria

• previous periodontal surgical treatment on the involved sites;
• smokers
• pregnants or lactating
• compromised systemic health and contraindications for periodontal surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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18 participants in 2 patient groups, including a placebo group

Test Group

Active Comparator group

Description:

Active comparator: gingival recession the aim of this study is to compare if the collagen matrix graft is as efficient as a substitute for the connective graft used in root coverage of gingival recessions

Treatment:

Procedure: Root coverage with collagen matrix graft

Other: Basic periodontal treatment

Control Group

Placebo Comparator group

Description:

the aim of this study is to compare if the collagen matrix graft is as efficient as a substitute for the connective graft used in root coverage of gingival recessions. The control group was treated with the same technique as the collagen matrix graft.

Treatment:

Procedure: Root coverage with subepithelial connective tissue graft

Other: Basic periodontal treatment