Mucosal Microbiome in Human Gastric Intestinal Metaplasia and Duodenal Tissue.

Shandong University

Status: Unknown

Conditions: Duodenum; Mucosal Microbiome; Gastric Intestinal Metaplasia

Treatments: Other: endomicroscopy, targeted biopsy and 16s rRNA gene sequencing

Study type: Observational

Funder types: Other

Identifiers

NCT02428426

2015SDU-QILU-G04

Details and patient eligibility

About

To investigate the mucosal microbiome in human gastric intestinal etaplasia and duodenal tissue.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients scheduled for gastroendoscopy examination Aged between 18 and 80 years old

Exclusion criteria

• Antibiotic, probiotic or prebiotic usage within 2months,gastric inhibitor usage within 1 month Esophageal, gastric or duodenal cancer or other malignancy History of upper GI tract surgery Coagulopathy or bleeding disorders Allergy to fluorescein sodium Pregnant or breast-feeding (for females) Impaired renal function

Trial design

20 participants in 2 patient groups

gastric intestinal metaplasia

Description:

patients were diagnosed gastric intestinal metaplasia

Treatment:

Other: endomicroscopy, targeted biopsy and 16s rRNA gene sequencing

gastritis

Description:

patients were diagnosed non atrophic gastritis

Treatment:

Other: endomicroscopy, targeted biopsy and 16s rRNA gene sequencing