Multi-center Research Project for Glioma Molecular Pathology Intraoperative Rapid Detection

Jinsong Wu

Status: Completed

Conditions: Glioma, Malignant

Treatments: Diagnostic Test: Intraoperative Rapid Detection mutation of IDH, TERT and BRAF v600e

Study type: Observational

Funder types: Other

Identifiers

NCT04904419

KY2020-1298

Details and patient eligibility

About

We explores the accuracy and sensitivity of rapid intraoperative detection of IDH, TERT, BRAF indicators through a prospective clinical multi-center study. This part includes a total of 300 fresh tissue samples, paired blood samples, relevant clinical information and follow-up information from 300 patients with different grades of adult glioma. By comparing with the postoperative sequencing results, the specificity and sensitivity of intraoperative IDH and TERT rapid detection results are clear.

Enrollment: 137 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Glioma patients with Informed Consent Form 2. Glioma patients with intact clinical information

Exclusion criteria

• 1. Glioma patients without Informed Consent Form 2. Glioma patients without intact clinical information