Multi-channel aEEG in Cardiac Arrest Patients With Targeted Temperature Management (MAEGIC)

Sang Hoon Oh

Status: Unknown

Conditions: Heart Arrest; Targeted Temperature Management

Treatments: Diagnostic Test: Multi-channel aEEG monitoring

Study type: Observational

Funder types: Other

Identifiers

NCT03545828

MAEGIC-01

Details and patient eligibility

About

This study aims to examine the prognostic value of 18 channel amplitude-integrated EEG (aEEG) in comatose cardiac arrest patients The study design is a prospective observational study. Cardiac arrest patients undergoing targeted temperature management (TTM) will participate in the study. Relation of aEEG in each channel with the neurologic outcome at 6 month after return of spontaneous circulation (ROSC) will be evaluated.

Full description

Normal trace was defined as continuous cortical activity on the raw EEG scan; in addition, the upper margin of the aEEG scan, referred to as the aEEG maximum, was >10 μ V, and the lower margin of the aEEG scan, referred to as the aEEG minimum, was >5 μ V. The Time from ROSC to normal trace (TTNT, hours) is predictor of neurological outcome in these patients. We will evaluate the prognostic values of TTNTs in all aEEG channels.

Enrollment: 78 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Comatose cardiac arrest TTM treatment Multi channel aEEG monitoring

Exclusion criteria

Cerebral origin cardiac arrest Known epilepsy

Trial design

78 participants in 2 patient groups

Good neurological outcome

Description:

CPC 1 and 2 at 6 month after ROSC

Treatment:

Diagnostic Test: Multi-channel aEEG monitoring

Poor neurological outcome

Description:

CPC 3 to 5 at 6 month after ROSC

Treatment:

Diagnostic Test: Multi-channel aEEG monitoring