Multi Detector-Row Computed Tomography (MDCT) Calcium Score of Heart Transplanted Patients

University of Oslo (UIO)

Status: Completed

Conditions: Coronary Artery Disease

Treatments: Procedure: MDCT calcium score

Study type: Interventional

Funder types: Other

Identifiers

NCT00294853

S-05099

Details and patient eligibility

About

The purpose of the study is to determine if calcium score can be used as a predictor of coronary artery disease in heart transplanted patients, as it is used in non-transplanted persons.

Full description

Several studies have shown that a negative calcium score is a strong independent negative predictor of coronary artery disease (CAD). CAD in heart transplants (HTx) differs from CAD lesions in native hearts. The aim of this study is to see if there is a similar relation between coronary artery calcium and CAD in transplanted hearts as in native hearts.

Enrollment: 240 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Heart transplanted patient
• Aged 18 or above.

Exclusion criteria

• Pregnancy
• Atrial fibrillation
• Severe heart failure New York Heart Association (NYHA) class IV
• Severe pulmonary disease making the patient unable to hold his/her breath for more than 10 seconds.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)